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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Curr Opin Endocrinol Diabetes Obes. 2013 Oct;20(5):449–454. doi: 10.1097/01.med.0000433063.78799.c2

Figure 2.

Figure 2

Serum TSH concentration after 8 weeks of brand name LT4 vs. generic formulation. Closed circles denote patients with congenital hypothyroidism; open circles indicate patients with acquired hypothyroidism. Lines connect paired data. The horizontal bar indicates the median value. The serum TSH concentration was significantly greater after generic vs. brand name product only in patients with CH [24*]. (Republished with permission of The Endocrine Society from Carswell JM, Gordon JH, Popovsky E et al. Generic and brand-name L-thyroxine are not bioequivalent for children with severe congenital hypothyroidism. J Clin Endocrinol Metab 2013; 98:610–617; permission conveyed through Copyright Clearance Center, Inc.)