. 2014 Apr 3;146(2):476–495. doi: 10.1378/chest.14-0527

TABLE 12 .

] Trends Over Time by Underlying Cause of Death Among Decedents With Reported PH

Disease Category: ICD-10 Codes	2001		2010		AAPC
Disease Category: ICD-10 Codes	Rate/100,000	% of Total PH Deaths	Rate/100,000	% of Total PH Deaths	AAPC
Diseases of the circulatory system
Pulmonary hypertension: I27.0, I27.2, I27.8, I27.9	1.63	29.3	1.95	30.2	1.5
Coronary heart disease: I20-I25	0.48	8.8	0.66	10.3	3.8^a
Valvular heart disease, nonrheumatic: I34-I38	0.14	2.6	0.25	4.1	6.7^a
Aortic stenosis: I06.0, I35.0, I35.2	0.04	0.9	0.10	1.6	10.8^a
Hypertension: I10-I15	0.04	1.0	0.10	1.6	9.2^a
Rheumatic heart disease: I00-I09	0.07	1.4	0.10	1.5	3.2^a
Pulmonary embolism: I26	0.07	1.3	0.04	0.7	−7.2^a
Heart failure: I50	0.03	0.6	0.02	0.4	−3.6^a
Other cardiovascular/cerebrovascular disease: I27.1, I28-I33, I40-I49, I51-I78	0.21	3.6	0.23	3.7	2.0
Respiratory disorder or infection
Chronic lower respiratory disease: J40-J47	1.46	26.2	1.24	19.0	−1.3^a
Emphysema only: J43	0.24	4.2	0.08	1.4	−8.7^a
Interstitial lung disease: J84	0.24	4.5	0.31	4.9	4.5^a
Influenza and pneumonia: J09-J18	0.04	0.9	0.07	1.2	5.5^a
All other respiratory diseases: J00-06, J20-J39, J60-J70, J85-J98	0.08	1.7	0.12	1.9	3.3^a
Autoimmune diseases: M5-M6, M8, M30-35	0.07	1.3	0.16	2.4	10.9^a
Congenital malformations, deformation, and chromosomal abnormalities: Q00-Q99	0.17	3.0	0.11	1.6	−5.2^a
Malignant neoplasms of the trachea, bronchus, and lung: C34	0.09	1.8	0.09	1.5	0.1
Diabetes mellitus: E10-E14	0.05	1.0	0.09	1.5	7.6^a
Nephritis, nephrotic syndrome, and nephrosis: N00-N07, N17-N19, N25-N27	0.03	0.7	0.07	1.1	9.2^a
Chronic liver disease and cirrhosis: K70, K73-74	0.02	0.3	0.05	0.8	17.0^a
Malignant neoplasms of lymphoid, hematopoietic, and related tissue: C81-C96	0.02	0.4	0.04	0.7	6.4^a
Sleep apnea: G47.3	…	0.1	0.04	0.6	NA
Certain conditions originating in the perinatal period: P00-P96	0.05	1.0	0.01	0.1	−12.5^a
Total	5.5	…	6.5	…	…

NA = not applicable; PH = pulmonary hypertension. See Table 2 and 5 legends for expansion of other abbreviations.

P < .05.