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. Author manuscript; available in PMC: 2014 Aug 5.
Published in final edited form as: Am J Med Sci. 2013 Jun;345(6):431–436. doi: 10.1097/maj.0b013e318294457f

Table 5. The Prevalence of HLA-B27 for U.S. Adults Ages 20-69 Years, by Selected Characteristics, NHANES 2009*.

Selected Characteristic n N % SE 95% CI
Overall U.S. Prevalence 124 2320 6.1 0.8 (4.6-8.2)
Gender
Males 53 1123 5.8 1.0 (3.9-8.4)
Females 71 1197 6.5 1 (4.7-8.9)
Race/Ethnic Groups
Non-Hispanic Whites 79 1021 7.5 1.2 (5.3-10.4)
Mexican-Americans 27 622 4.6 0.6 (3.4-6.1)
Non-Hispanic Blacks 4 345 1.1* 0.5* (0.4-3.1)*
Age Groups
20-29 Years 39 498 8.0 2.0 (4.6-13.4)
30-39 years 26 471 5.6 1.3 (3.4-9.2)
40-49 Years 34 508 8.1 1.2 (5.8-11.2)
50-59 Years 11 404 2.9** 0.9** (1.4-5.8)**
60-69 Years 14 439 4.6** 1.9** (1.9-10.7)**
*

This is an estimate, as the small numbers lack statistical power to derive a definitive frequency

**

Multiple logistic regression analysis of the independent effects of gender, race/ethnicity and age group showed significantly lower HLA-B27 prevalence estimates for older as opposed to younger U.S. adults (3.6% for those 50-69 years of age vs. 7.3% for those 20-49 years, respectively (OR 0.4, 95% CI 0.3-0.8).