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. 2014 Aug 5;9(8):e101970. doi: 10.1371/journal.pone.0101970

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© 2014 Sinha, Rae

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The effect of insulin signaling genes identified as being integral for survival towards X. nematophila from genome wide analysis. Survival of C. elegans glp-1(e2141); empty vector control (blue) n = 100 (2 independent replicates), glp-1(e2141); daf-16 (RNAi) (red) n = 100 (2) and glp-1(e2141); daf-18 (RNAi) (green) n = 100 (2) when exposed to X. nematophila. (B) The effect of proteasomal complex genes identified as being integral for survival towards X. nematophila from genome wide analysis. Survival of C. elegans glp-1(e2141); empty vector control (blue) n = 100 (2), glp-1(e2141); rpn-6.1 (RNAi) (red) n = 100 (2), glp-1(e2141); rpn-7 (RNAi) (green) n = 60 (2), glp-1(e2141); pbs-6 (RNAi) (purple) n = 100 (2), glp-1(e2141); rpn-10 (RNAi) (turquoise) n = 100 (2), glp-1(e2141); rpt-6 (RNAi) (orange) n = 100 (2) and glp-1(e2141); pbs-4 (RNAi) (light blue) n = 100 (2) when exposed to X. nematophila. (C) The effect of new genes identified as being integral for survival towards X. nematophila from genome wide analysis. Survival of C. elegans glp-1(e2141); empty vector control (blue) n = 100 (2), glp-1(e2141); T12G3.6 (RNAi) (purple) n = 100 (2), and glp-1(e2141); par-5 (RNAi) (orange) n = 60 (2) when exposed to X. nematophila.