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. 2014 Aug 5;9(8):e104020. doi: 10.1371/journal.pone.0104020

Figure 7. Ang II upregulates TLR4 expression in SHR VSMCs via the AT1 receptors.

Figure 7

(A) Effect of Ang II (100 nM, 15 min-3 h) on TLR4 mRNA levels in SHR VSMCs. (B) Effect of Ang II (2 h) on TLR4 mRNA levels in the absence and the presence of losartan (10 µM, 1 h). The results (mean±SEM) are expressed as relative expression compared with control. *P<0.05 vs Control, #P<0.05 vs Ang II by Student’s t-test. n = 4–5.