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. 2014 Jul 25;9:3527–3538. doi: 10.2147/IJN.S63507

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© 2014 Cai et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Schematic illustrations of different release behaviors of rhGH from rhGH alone loaded hydrogel (A) and PLA/rhGH complex-loaded hydrogel (B), which can inhibit the initial burst.

Note: Reprinted from Journal of Controlled Release, 147(3), Park MR, Chun C, Ahn SW, Ki MH, Cho CS, Song SC, Sustained delivery of human growth hormone using a polyelectrolyte complex-loaded thermosensitive polyphosphazene hydrogel, pages 359–367.³² Copyright © 2010, with permission from Elsevier.

Abbreviations: PLA, poly(lactic acid); hGH, human growth hormone; rhGH, recombinant human growth hormone.