Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 25;9:3539–3550. doi: 10.2147/IJN.S65287

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Subongkot et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Transmission electron microscopy images of pig skin treated with ultradeformable liposomes, obtained from ultrathick section of pig skin treated with ultradeformable liposomes at 4 hours.

Notes: (A) Corneodesmosome degradation (black arrow) between SC and SG; scale bar represents 0.5 μm. (B) Corneodesmosome degradation (black arrow) and disintegrated particle (white arrow) between SC and SG; scale bar represents 0.2 μm. (C) Desmosome in viable epidermis; scale bar represents 0.2 μm. (D) Hemidesmosome at stratum basale and papillary dermis; scale bar represents 0.2 μm. (E) Ultradeformable liposome penetration into the skin (black arrow); scale bar represents 5 μm. (F) Magnification of marked area in (E); scale bar represents 0.2 μm. (G) Disrupted cell membrane (black arrow) from penetration of intact vesicles into SG; scale bar represents 0.5 μm. (H) Magnification of (G); scale bar represents 0.2 μm.

Abbreviations: SC, stratum corneum; SG, stratum granulosum; SB, stratum basale; PD, papillary dermis; D, desmosome; CD, corneodesmosome; HD, hemidesmosome; VE, viable epidermis.