Table 4. Odds ratio (OR) for the progression of attachment loss (AL) according to leukotoxicity.

Variable	OR	95% CI	p-values	Individuals,total number(n)	Individuals, withprogression ofAL≥3 mm, n (%)
Cell lysis
minimal	4.1	2.3–7.3	<0.001	110	41 (37.3)
Average + high	10.9	4.9–24.1	<0.001	36	22 (61.1)
Cell death
Minimal + average	4.3	2.4–7.7	<0.001	97	37 (38.1)
high	7.8	3.9–15.8	<0.001	49	26 (53.1)
Haemolysis
minimal	4.8	2.6–8.8	<0.001	90	37 (41.1)
average	3.9	1.8–8.5	<0.001	39	14 (35.9)
high	16.6	5.4–51.3	<0.001	17	12 (70.9)
A.a * negative	1.0	reference		190	24 (12.6)

Cell lysis (minimal = 0–30%, average + high = ≥31% release of cytosolic LDH), Cell death (minimal + average = 0–60%, high = ≥61% reduction of viable cells), Haemolysis (1 = minimal, none or small zone, 2 = average, average size zone, 3 = high, large size zone). Subgroup of individuals (n = 146) positive for A. actinomycetemcomitans. The reference group consisted of individuals (n = 190) who were negative for A. actinomycetemcomitans. OR, odds ratio; confidence interval; AL, attachment loss. Significance (p<0.05).

*A.a; A. actinomycetemcomitans.