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. 2014 Aug 5;9(8):e104378. doi: 10.1371/journal.pone.0104378

Figure 2. GGAA-microsatellite organization at the NR0B1 locus.

Figure 2

(A) Using available single nucleotide polymorphism (SNP) data from the CEU reference population (northern and western European decent) of the International HapMap Project [24], the NR0B1 GGAA-microsatellite is identified within a defined haplotype block. (B) For the NR0B1 locus, the GGAA-microsatellite is located approximately 1.5 kb upstream of the transcriptional start site (TSS) and is characterized a variable number of contiguous GGAA motifs, partitioned by single adenosine base substitutions. Sequence characteristics of interest include the total number of GGAA motifs, the total number of contiguous segments and longest consecutive GGAA segment. Figure panel adapted from [12].