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. 2014 Aug 5;9(8):e104378. doi: 10.1371/journal.pone.0104378

Figure 6. NR0B1 GGAA-microsatellite polymorphisms do not influence event free survival (EFS) in Ewing sarcoma patients.

Figure 6

(A) EFS was compared in 112 patients from AEWS0031 based on the presence of absence of at least one NR0B1 GGAA-microsatellite allele containing 22–27 GGAA motifs. This allele type was chosen based on the pattern of alleles present in tumor samples and the maximal EWS/FLI-mediated gene expression supported by alleles of this length category. (B) EFS was similarly assessed based on the presence of one or both alleles containing 22–27 GGAA motifs. Additional subgroup analyses were also performed in males (C) and females (D) and in patients receiving standard (E) or compressed (F) therapy.