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. 2014 Aug 5;9(8):e104172. doi: 10.1371/journal.pone.0104172

Figure 3. Neonatal overexposure to NRG1 but not NRG3 impairs sensorimotor gating in adulthood.

Figure 3

The effect of daily treatment from PND 2–10 with 3 mg/kg NRG3-EGF (A, B) or 1 mg/kg NRG1-EGF (C, D) on startle responses to the presentation of no stimulus or a 120 dB stimulus (A, C) and % prepulse inhibition of the startle response to the presentation of prepulse stimuli at amplitudes of 74, 78, 82, 86 and 90 dB (B, D) in adulthood. Data represents mean ± s.e.m., n = 8–14/treatment group. **p<0.01, main effect of treatment.