Table 3. Expression of phase 2 antigen and phase variation frequency.
Genotypea | Selectability | Phase variation | ||
Parental strain | fljA | hin | of phase 2b | frequencyc |
L-3900 | WT | WT | + | 1.84×10−4 |
A46T | WT | + | 9.11×10−5 * | |
WT | R140L | - | <10−6 | |
A46T | R140L | - | <10−6 | |
L-3287 | WT | WT | + | <10−6 |
A46T | WT | - | ND | |
WT | R140L | - | ND | |
A46T | R140L | - | ND |
WT, wild type; A46T and R140L, amino acid substitutions.
+, selectable; -, not detected.
ND, not done;
*, significantly lower than parental strain (p = 0.04).