Table 2. AKI mRNA signature as verified in the independent evaluation dataset.
| post-TX | baseline adjusted | |||||
| Probe Set ID | Gene Symbol | raw p-value | Fold change | raw p-value | Fold change | Gene Description |
| 16919547 | SLPI | 1.55E-03 | 5.67 | 1.20E-03 | 15.17 | secretory leukocyte peptidase inhibitor |
| 16775083 | OLFM4 | 6.15E-03 | 2.86 | 2.98E-03 | 7.88 | olfactomedin 4 |
| 16787902 | SERPINA3 | 1.08E-03 | 2.03 | 2.91E-03 | 7.03 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| 16743647 | MMP7 | 3.42E-02 | 2.88 | 1.54E-02 | 4.06 | matrix metallopeptidase 7 (matrilysin, uterine) |
| 16760792 | CD163 | 2.77E-02 | 1.94 | 1.69E-02 | 3.12 | CD163 molecule |
| 16693414 | S100A8 | 7.43E-04 | 2.40 | 1.66E-02 | 3.09 | S100 calcium binding protein A8 |
| 16735751 | LYVE1 | 7.55E-04 | 1.53 | 2.09E-03 | 2.28 | lymphatic vessel endothelial hyaluronan receptor 1 |
| 17089525 | LCN2 | 5.02E-03 | 1.95 | 8.81E-03 | 2.28 | lipocalin 2 |
| 16707503 | EXOC6 | 8.75E-04 | 1.52 | 1.88E-03 | 1.78 | exocyst complex component 6 |
| 17024144 | IFNGR1 | 4.61E-03 | 1.51 | 7.64E-03 | 1.77 | interferon gamma receptor 1 |
| 17087615 | LPPR1 | 5.54E-04 | 0.51 | 3.00E-03 | 0.57 | lipid phosphate phosphatase-related protein type 1 |
| 16991527 | CYFIP2 | 2.00E-03 | 0.55 | 2.80E-03 | 0.52 | cytoplasmic FMR1 interacting protein 2 |
| 16695262 | KCNJ10 | 3.92E-04 | 0.55 | 3.00E-04 | 0.52 | potassium inwardly-rectifying channel, subfamily J, member 10 |
| 17101262 | ARSF | 1.46E-03 | 0.57 | 3.30E-03 | 0.47 | arylsulfatase F |
| 17094946 | TRPM6 | 1.89E-02 | 0.62 | 2.19E-03 | 0.45 | transient receptor potential cation channel, subfamily M, member 6 |
| 17072059 | SLC30A8 | 2.29E-02 | 0.53 | 4.78E-03 | 0.45 | solute carrier family 30 (zinc transporter), member 8 |
| 16773086 | FGF9 | 4.37E-04 | 0.55 | 8.50E-04 | 0.45 | fibroblast growth factor 9 (glia-activating factor) |
| 16934643 | PVALB | 2.02E-04 | 0.39 | 2.75E-03 | 0.42 | parvalbumin |
| 17007950 | PNPLA1 | 1.15E-03 | 0.50 | 1.10E-03 | 0.36 | patatin-like phospholipase domain containing 1 |
| 16962671 | TMEM207 | 1.57E-04 | 0.32 | 9.31E-04 | 0.33 | transmembrane protein 207 |
bold......molecular features discussed as biomarker candidates of acute kidney injury.
Raw p-values and fold changes of verified differentially regulated genes are provided.