Table 1. Clinical characteristics of study population.
Type 2 diabetes | Control | P | |
N | 5338 | 4663 | |
Male, % | 43.3 | 32.2 | <0.0001 |
Age, year | 56.0 (47.0, 64.0) | 49.0 (44.0, 56.0) | <0.0001 |
Body weight, kg | 66.1 (59.0, 75.0) | 59.1 (54.0, 65.0) | <0.0001 |
BMI, kg/m2 | 25.6 (23.4, 28.2) | 23.1 (21.3, 24.8) | <0.0001 |
Waist circumference, cm | 88.0 (81.0, 95.0) | 79.0 (73.0, 85.0) | <0.0001 |
Fasting plasma glucose, mmol/l | 7.3 (6.2, 9.0) | 5.0 (4.7, 5.4) | <0.0001 |
30-min OGTT glucose, mmol/l | 11.9 (9.8, 14.3) | 8.1 (7.0, 9.2) | <0.0001 |
2-h OGTT glucose, mmol/l | 13.4 (11.2, 17.0) | 5.8 (4.9, 6.6) | <0.0001 |
Fasting serum insulin, mU/l | 8.7 (6.1, 12.6) | 6.3 (4.9, 8.5) | <0.0001 |
30-min OGTT insulin, mU/l | 20.1 (11.5, 36.3) | 32.9 (21.0, 52.5) | <0.0001 |
2-h OGTT insulin, mU/l | 32.2 (18.6, 60.4) | 22.2 (13.7, 35.0) | <0.0001 |
HOMA-B, % | 47.0 (28.0, 77.0) | 85.5 (61.0,125.6) | <0.0001 |
Insulinogenic index | 2.9 (1.3, 6.3) | 9.4 (5.0, 17.3) | 0.0032 |
HOMA-IR | 3.0 (1.9, 4.6) | 1.4 (1.1, 1.9) | <0.0001 |
ISIm | 4.3 (2.9, 6.3) | 8.4 (6.2, 11.3) | <0.0001 |
Abbreviations: BMI, body mass index; OGTT, oral glucose tolerance test; ISIm, Matsuda index.
Data are shown as median (interquartile range) or %.