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. 2014 Aug 5;9(8):e104486. doi: 10.1371/journal.pone.0104486

Table 3. Joint effects of obesity-related risk alleles on the risk for type 2 diabetes in study population.

Quartile Model 1 Model 2 Model3
OR (95%CI) P OR (95%CI) P OR (95%CI) P
Q1 1 1 1
Q2 1.24 (1.08,1.43) 2.60E-03 1.28 (1.10,1.50) 2.00E-03 1.28 (1.09,1.50) 2.10E-03
Q3 1.19 (1.03,1.37) 1.87E-02 1.19 (1.01,1.39) 3.37E-02 1.17 (0.99,1.37) 5.90E-02
Q4 1.29 (1.10,1.51) 1.40E-03 1.18 (1.00,1.41) 5.72E-02 1.18 (0.99,1.40) 6.85E-02
P trend 4.80E-03 1.21E-01 1.66E-01

Abbreviations: OR, odds ratio; CI, confidence interval; BMI, body mass index; WC, waist circumference.

OR and 95% CI are reported for genotype risk score quartiles using logistic regression under the following models: model 1, adjusted for age and sex; model 2, adjusted for age, sex and BMI; and model 3, adjusted for age, sex, BMI and WC.

P values<0.05 are shown in bold.