Table 3. Joint effects of obesity-related risk alleles on the risk for type 2 diabetes in study population.
Quartile | Model 1 | Model 2 | Model3 | |||
OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | P | |
Q1 | 1 | 1 | 1 | |||
Q2 | 1.24 (1.08,1.43) | 2.60E-03 | 1.28 (1.10,1.50) | 2.00E-03 | 1.28 (1.09,1.50) | 2.10E-03 |
Q3 | 1.19 (1.03,1.37) | 1.87E-02 | 1.19 (1.01,1.39) | 3.37E-02 | 1.17 (0.99,1.37) | 5.90E-02 |
Q4 | 1.29 (1.10,1.51) | 1.40E-03 | 1.18 (1.00,1.41) | 5.72E-02 | 1.18 (0.99,1.40) | 6.85E-02 |
P trend | 4.80E-03 | 1.21E-01 | 1.66E-01 |
Abbreviations: OR, odds ratio; CI, confidence interval; BMI, body mass index; WC, waist circumference.
OR and 95% CI are reported for genotype risk score quartiles using logistic regression under the following models: model 1, adjusted for age and sex; model 2, adjusted for age, sex and BMI; and model 3, adjusted for age, sex, BMI and WC.
P values<0.05 are shown in bold.