Table 1. Biodistribution of GLV-5b451 in virus-treated mice bearing DT09/06 xenografts at 28 days post virus injection (dpvi).

PFU per gram (g) of organ or tumor tissue	DT09/06 xenografts treated with 1×107 pfu GLV-5b451
Mouse No	288	290	337
Tumor	4.66E+07	1.35E+07	4.39E+07
Lung	1.72E+02	7.6E+02	n.d.
Liver	6.94E+03	7.29E+03	2.62E+02
Spleen	1.75E+02	8.33E+03	4.33E+02
Kidney	1.5E+03	4.71E+02	1.0E+02
Ovaries	1.6E+03	n.d.	n.d.

The data were determined by standard plaque assay on CV-1 cells using aliquots of the homogenized organs and were displayed as mean pfu per gram of organ or tissue. For each organ, two aliquots of 0.1 ml were measured in triplicates.

n. d.: not detected (detection limit <10 pfu/organ).