Table 1.
Patient and transplantation characteristics
|
Early graft function (EGF) n = 110 (62.5%) |
Delayed graft function (DGF) n = 66 (37.5%) |
p-value | |
|---|---|---|---|
|
Mean recipient age years (SD) |
50.4 (12.8) |
54.4 (13.2) |
NS |
|
Gender, male (%) |
65 (59.1) |
45 (68.2) |
NS |
|
Re-transplantation (%) |
8 (7.3%) |
7 (10.6%) |
NS |
|
Mode of dialysis, hemodialysis (%) |
63 (57.3%) |
51 (77.3%) |
0.009 |
|
Time on dialysis before transplantation, days (SD) |
788 (570.3) |
953 (608.7) |
0.029 |
|
Mean donor age years (SD) |
49.1 (14.6) |
56.2 (11.5) |
0.001 |
|
Expanded criteria donors |
33 (30.0%) |
36 (54.5%) |
0.001 |
|
Mean cold ischemia time, hours (SD) |
21.3 (3.5) |
22.9 (3.7) |
0.003 |
|
Day 1 mean plasma creatinine, μmol/L (SD) |
464 (218.4) |
207 (114.4) |
<0.0001 |
|
Day 1 mean urine output, mL/24 hours (SD) |
2504 (1514.8) |
502 (538.5) |
<0.0001 |
|
Number of rejections |
5 (4.5%) |
5 (7.5%) |
NS |
|
Mean eGFR, mL/min at 1 year (SD) |
66.2 (20.1) |
54.8 (20.5) |
<0.0001 |
|
1-year patient survival |
99.1% |
98.5% |
NS |
| 1-year graft survival | 98.2% | 89.4% | 0.015 |
eGFR = estimated glomerular filtration rate calculated using the MDRD equation. SD = standard deviation. Delayed graft function defined according to the conventional definition: i.e. the need for dialysis during the first week after transplantation. Expanded criteria donor status defined according to Port et al. [28].