Table 7.
Time from reperfusion to day 1 serum sampling
| Sample time after reperfusion | Mean sNGAL ng/ml EGF (SD) | Mean sNGAL ng/ml DGF (SD) | p-valueDGF vs EGF | ROC-analysis AUC, p-value, CIoptimal cut-off value, sensitivity, specificity |
|---|---|---|---|---|
| <6 hours |
n = 9 |
n = 9 |
0.002 |
1.00, p = 0.001, CI 1.00-1.00 |
| |
278 (78.8) |
687 (239.4) |
|
436 ng/ml, 100%, 100% |
| 7 to 12 hours |
n = 46 |
n = 36 |
<0.0001 |
0.864, p < 0.0001, CI 0.783-0.946 |
| |
365 (159.5) |
594 (169.2) |
|
420 ng/ml, 94%, 73% |
| >12 hours |
n = 47 |
n = 23 |
<0.0001 |
0.920, p < 0.0001, CI 0.838-0.999 |
| 321 (125.0) | 526 (187.9) | 420 ng/ml, 91%, 83% |
EGF = early graft function, DGF = delayed graft function, AUC = area under the curve, CI = confidence interval. Delayed graft function defined according to the conventional definition: i.e. the need for dialysis during the first week after transplantation.