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. Author manuscript; available in PMC: 2015 Sep 5.
Published in final edited form as: Neuroscience. 2014 Jun 17;275:184–193. doi: 10.1016/j.neuroscience.2014.06.012

Figure 4.

Figure 4

In vivo non-photic phase resetting of the SCN circadian clock. A. Representative double-plotted actograms of general locomotor activity showing phase-advance shifting in response to acute cocaine (20 mg/kg i.p. ) in wild-type mice (bottom left panel) that was not expressed in SERT Met172 mutant mice (bottom right panel) or in saline injected controls (top panels). B. Histogram representation (means ± SEM) of behavioral rhythm data showing the phase-resetting action of acute cocaine (20 mg/kg i.p.) in wild-type mice (WT) but not in SERT Met172 mutant mice. Saline injections had little phase-resetting effect. Bars with different letters are significantly different (p<0.05). See Fig 1 legend for details.