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. Author manuscript; available in PMC: 2014 Sep 10.
Published in final edited form as: Stat Med. 2014 Feb 27;33(20):3509–3527. doi: 10.1002/sim.6120

Table 3.

GMM Analysis Results of the Application Example

Estimation Procedu
Reference Group
3-step Hybrid
RSG
3-Step Hybrid
SU+MET
3-Step
Poor Control Stratum (22%) Estimate & 95% CI
Baseline HbA1c 8.55 (8.42,8.68) 8.41 (8.33,8.49) 8.45 (8.30,8.60)
Post-treatment HbA1c 8.60 (8.41,8.78) 8.38 (8.25,8.50) 8.49 (8.27,8.71)
RSG Effect on HbA1c 0.36 (0.00,0.72) 0.23 (−0.08,0.54) −0.07 (−0.36,0.22)
RSG Effect on CVD (Odds Ratio) 0.28 (0.09,0.83) 0.35 (0.15,0.83) 0.37 (0.16,0.85)
RSG Effect on Death (Odds Ratio) 0.66 (0.28,1.51) 0.70 (0.36,1.37) 0.84 (0.44,1.61)

Better Control Stratum (78%) Estimate & 95% CI
Baseline HbA1c 7.23 (7.20,7.25) 7.17 (7.14,7.19) 7.18 (7.14,7.22)
Post-treatment HbA1c 7.00 (6.96,7.03) 6.95 (6.92,6.98) 6.96 (6.92,7.01)
RSG Effect on HbA1c 0.09 (0.01,0.16) 0.09 (0.01,0.17) 0.07 (−0.01,0.15)
RSG Effect on CVD (Odds Ratio) 0.76 (0.55,1.06) 0.77 (0.55,1.08) 0.77 (0.55,1.07)
RSG Effect on Death (Odds Ratio) 1.18 (0.88,1.57) 1.19 (0.88,1.60) 1.15 (0.86,1.56)