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Genomic differences in patients with AD before and after CsA treatment. Significant changes in differentially-expressed genes/DEGs defining the AD transcriptome (A) occur by wk2 in NL and LS skin (B). Heatmaps are arranged by patient SCORAD (white-to-black gradient); pink=patients with unknown SCORAD. Red/upregulated; Blue/downregulated; AD/atopic dermatitis; Wk/week; LS/lesional; NL/non-lesional; FCH/fold-change.
