Table 1.
Baseline, nadir, and maximal cutaneous vascular conductance
| Baseline CVC, %max |
Nadir CVC, %max | Maximal CVC, mV/MAP·100 |
|||||
|---|---|---|---|---|---|---|---|
| Protocol 1 | Protocol 2 | Protocol 3 | Protocol 2 | Protocol 1 | Protocol 2 | Protocol 3 | |
| Control | 6.9 ± 2.1 | 8.7 ± 1.4 | 7.7 ± 1.1 | 24.4 ± 3.3 | 192.6 ± 7.9 | 220 ± 20 | 294 ± 37 |
| TEA | 5.5 ± 0.9* | 3.9 ± 0.4* | 11.3 ± 2.1* | 213 ± 18 | 351 ± 43 | ||
| L-NAME | 4.9 ± 0.6* | 5.9 ± 0.7* | 8.1 ± 1.2* | 209 ± 23 | 269 ± 28 | ||
| TEA+L-NAME | 3.3 ± 0.4* | 4.4 ± 1.0* | 5.0 ± 0.6*† | 200 ± 16 | 285 ± 33 | ||
Drugs include tetraethylammonium (TEA) and nitro-L-arginine methyl ester (L-NAME); CVC, cutaneous vascular conductance. Data are means ± SE. Data for protocol 1 are pooled data across all nine combinations of rates of local heating target temperatures.
P < 0.05 compared with the Control site within each protocol;
P < 0.05 compared with the TEA site within each Protocol.