Table 1.
Passive and active membrane properties of layer II/III and V/VI PNs located in the prelimbic region of the PFC
| Layer II/III | Layer V/VI | P value | |
|---|---|---|---|
| RMP, mV | −67.9 ± 1 | −69.5 ± 1 | 0.21 |
| Input resistance, MΩ | 156 ± 9 | 102 ± 9 | <0.001 |
| Membrane capacitance, pF | 176 ± 7 | 170 ± 13 | 0.73 |
| τm, ms | 28 ± 2 | 16 ± 1 | <0.001 |
| Rheobase, pA | 111 ± 10 | 155 ± 14 | <0.05 |
| Sag, mV | 2.7 ± 0.4 | 4.0 ± 0.5 | <0.05 |
| ADP, mV | 3.2 ± 0.4 | 3.5 ± 0.4 | 0.61 |
Values are means ± SE; n = 30 for each group.
PN, pyramidal neuron; PFC, prefrontal cortex; RMP, resting membrane potential; τm, membrane time constant; ADP, afterdepolarization. P values, unpaired t-test; significant values are in boldface.