Fig. 3.

A: blood oxygen level-dependent (BOLD) activation increase associated with the wrist localizer task. Voxel-based and ROI analyses were masked by mean activation pattern for straight reaching movements with the left wrist (Localizer scan, wrist movements > baseline). Average activation patterns are shown on inflated brain surfaces. Average activation in the cerebellum is shown on a coronal slice (y = −50). Reaching movement with the wrist was associated with a broad increase in activation in both hemispheres, in visual and motor areas and in the cerebellum. B: contrast map for the Trained task. Subjects were scanned while performing the Trained horizontal arc task before and after training (on days 1 and 5). A contrast analysis between day 1 and day 5 activation patterns within the task mask (subset a) is shown. Increase in activation after training is shown in red-yellow colors; decrease in activation is shown in blue-green colors (color coding is shown at bottom right). Training in the APT was associated with increased activation in the right primary motor, premotor, and supplementary motor cortices. Reduction of activation after training was not detected. C: contrast map for the Untrained vertical arc task. A contrast analysis for the Untrained task within the task mask did not result in any significant change in activation. D: task × training interaction analysis. An interaction analysis (using ANCOVA) between training (day 1 vs. day 5) and task (Trained vs. Untrained) within the task mask resulted in significant activation in premotor dorsal and supplementary motor cortex.