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. 2014 Jul 28;14:266. doi: 10.1186/1472-6882-14-266

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© de Faveri Favero et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Determination of the allodynia score of Lac-FR in the CFA model of persistent pain. Graph demonstrating the decrease on allodynia score related to the touch stimulation exerted on the surface of the left and right hind paws caused by injection of saline solution and CFA (0.1 ml) respectively, producing persistent pain sensitization in rats treated with the Lac-FR (30, 100, and 300 mg/kg, i.p.), compared to the control group (vehicle, 10 ml/kg i.p.). Results expressed as reduction score means ± S.E.M. of 6 animals for experimental group (ANOVA and Bonferroni’s test. ***p < 0.001, *p < 0.05).