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. 2014 Jul 28;14:266. doi: 10.1186/1472-6882-14-266

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© de Faveri Favero et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Evaluation of the potential anti-inflammatory effects of Lac-FR. Effect of the Lac-FR on carrageenan-induced paw edema expressed as paw edema (mL) per time after inflammation induction. Mice were pretreated i.p. with Lac-FR (100 and 300 mg/kg), and vehicle (10 ml/kg i.p.), 30 min before the intraplantar 2.5% carrageenan injection. Paw edema was evaluated in plethysmometer 2, 4, 6, and 24 hours after inflammation induction. (ANOVA and Bonferroni’s test. ***p < 0.001, **p < 0.01; *p < 0.05).