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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: J Cell Physiol. 2008 Apr;215(1):77–81. doi: 10.1002/jcp.21289

Figure 2. Effects of EGF, AG1478 and TTX on Transwell migration of Mat-LyLu cells.

Figure 2

Migration index (MiI) values were expressed as percentages of the basal value in 0% FBS. A: Dose–response relationship for the effect of EGF (1–100 ng/ml) on percentage increase in MiI (ΔMiI). B: Effects of EGF (100 ng/ml), AG1478 (1 μM) and TTX (500 nM), and their specific combinations on MiI. Data are shown relative to the control value for 0% FBS (100%). Bars represent means and SEMs (n = 14). These data were consistent with the following: (1) Both EGF/EGFR and VGSC activity were involved in potentiating Mat-LyLu cell migration. (2) The EGF-stimulated enhancement of motility occurred partially via VGSC activity.