Table 1.

Characteristics of participants.

Participant	Age (years)	History of atopya	Smoking status	Sex	Height (cm)	Weight (kg)	BMI (kg/m2)	Asthma duration (years)	FEV1 at inclusion (FEV1 % predicted)	PD20 methacholine at baseline (μg)	Percent eosinophils in sputum at baselineb
1c	26	Yes	N	F	164	57	21	8	3.23 (110)	1,600	NA
2	29	No	E	M	185	90	27	11	4.13 (89)	1,490	14.73
3	29	No	N	M	182	87	27	10	4.43 (99)	690	11.88
4	31	No	N	M	161	84	33	8	2.87 (81)	3,200	6.79
5	28	No	N	M	174	74	25	4	3.69 (88)	1,550	1.68
6	27	No	N	M	180	88	28	21	3.57 (80)	1,220	0.93
7	24	No	N	M	178	70	22	8	3.88 (87)	1,070	4.25
8	30	No	N	F	159	56	22	20	3.03 (103)	500	2.68
9	29	Yes	N	M	168	72	26	22	3.89 (100)	3,200	1.88
10c	28	Yes	N	M	186	92	27	2	4.49 (96)	800	ANR
11	20	Yes	N	F	158	49	20	9	2.29 (76)	930	0.26
12	69	No	N	M	178	90	29	5	2.49 (78)	3,200	17.72
13	30	No	N	F	163	55	21	20	2.68 (87)	1,950	32.08
14	32	Yes	N	M	179	82	26	24	4.12 (92)	340	2.51
15	24	No	N	F	171	60	21	14	3.41 (97)	310	5.12
16	28	No	N	M	174	62	21	16	3.82 (91)	2,100	20.58
17	32	No	N	M	176	115	38	21	4.16 (100)	2,170	2.99
18c	30	Yes	N	M	169	89	32	21	3.75 (95)	190	NA
19	30	No	N	M	174	115	39	23	3.16 (76)	210	1.55
Abbreviations: ANR: available but not relevant because participant 10 did not complete the three series of exposure; E, ex-smoker; N, never-smoker; NA: not available. aPersonal history of atopic dermatitis and/or atopic familial history. bPercent eosinophils at baseline (10–30 days before first exposure). cParticipants excluded from the analysis: participants 1 and 18 did not produce adequate sputum specimens for cell analysis at baseline (squamous cells > 20%); participant 10 did not complete the three series of exposure.