Table 2.
GMs (95% CIs) of values relative to baseline of FEV1 and PEF evaluated in the 18 participants who completed the study.
Variable | 0 ppb NO2 (clean air) | 200 ppb NO2 | 600 ppb NO2 | p-Value |
---|---|---|---|---|
FEV1/baseline | 1.02 (1.00, 1.05) | 1.00 (0.97, 1.03) | 1.00 (0.98, 1.03) | 0.41 |
PEF/baseline | 1.05 (0.99, 1.11) | 1.04 (0.98, 1.10) | 1.01 (0.96, 1.07) | 0.36 |
Baseline values were measured immediately before first exposure (H0 on day 1) for each series of exposure. Each value corresponds to the GM change from baseline of the six values [H0’, immediately after first exposure (day 1); H6, 6 hr after H0’ (day 1); H32, 32 hr after H0’ (day 2); H48, 48 hr after H0’ (day 3)] obtained by spirometry with flow-volume curves. The effects of exposure, regardless of the dose, on FEV1 and PEF were not significant. |