Figure 7.

SH suppressed the growth of human breast tumors in vivo. Nude mice bearing MDA-MB-231 human breast xenografts were treated with physiological saline or SH at a low dose (75 mg/kg of body weight) or a high dose (150 mg/kg of body weight) for 21 days. (a) Body weight and (b) tumor volume were recorded every 3 days. (c) Representative tumor pictures are shown. (d) Tumor weight was evaluated on the twenty-first day. (e) Immunohistochemical staining of tumor specimens. Data are represented as mean±S.D. of six mice in each group. *P<0.05, ^#P<0.01, SH-treated group compared with the untreated control group