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Metabolic changes for GABA, NAA, glutamate and glutamine represented as ratios from the NMR spectra for the cortex brain region without any overlapping peaks
| C57 vs. mnd | C57 vs. nclf | 129 vs. Cln3 young | 129 vs. Cln3 old | |
|---|---|---|---|---|
| GABA/Glu | ↑0.04 | – | – | ↑0.05 |
| Gln/Glu | ↓0.03 | ↓0.05 | ↓0.002 | ↓0.02 |
| NAA/Glu | ↑0.008 | – | – | ↑0.05 |
A Student t test was carried out to determine the significance of the changes (reported for significant changes)
