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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: Amyloid. 2009 Mar;16(1):1–8. doi: 10.1080/13506120802676781

Figure 1.

Figure 1

An example of an alignment of selected amyloidogenic VL LC to closest germline progenitor. Each LC in the database can be aligned to its most likely germline gene progenitor. A substitution list is generated and the comparison can be presented visually using a coloured alignment. FRs and CDRs are distinguished by light grey and dark grey header lines, respectively.