Table 2.
Selected covariates and components of microvascular outcomes at baseline, by glycemia trial arm assignment.
| Parameter | N | Standard Glycemia Median (I-Q Range) | N | Intensive Glycemia Median (I-Q Range) | |
|---|---|---|---|---|---|
| Continuous Factors | HbA1c (%) | 5111 | 8.1 (1.3) | 5101 | 8.1 (1.3) |
| Fasting serum glucose (mmol/l) | 5090 | 9.27 (3.66) | 5080 | 9.33 (3.61) | |
| SBP (mmHg) | 5094 | 135 (22) | 5095 | 135 (22) | |
| DBP (mmHg) | 5094 | 75 (14) | 5095 | 75 (14) | |
| LDL cholesterol (mmol/l) | 5093 | 2.61 (1.14) | 5082 | 2.59 (1.14) | |
| HDL cholesterol in women (mmol/l) | 1969 | 1.16 (0.41) | 1953 | 1.16 (0.39) | |
| HDL cholesterol in men (mmol/l) | 3124 | 0.96 (0.28) | 3129 | 0.96 (0.31) | |
| Triglycerides (mmol/l) | 5093 | 1.76 (1.41) | 5082 | 1.74 (1.33) | |
| BMI (kg/m2) | 5116 | 31.9 (7.7) | 5112 | 31.7 (12.0) | |
| Serum creatinine (micromol/l) | 5081 | 79,6 (17.7) | 5093 | 79.6 (17.7) | |
| eGFR (mL/min/1.73m2) | 5081 | 90 (30) | 5093 | 90 (29) | |
| Urine albumin-creatinine ratio (mg/g) | 5071 | 13.6 (37.3) | 5083 | 13.6 (37.5) | |
| Average right/left eye visual acuity score | 4908 | 77 (13) | 4874 | 77 (13) | |
| Average right/left eye Snellen fraction | 4961 | 32 (17) | 4933 | 32 (19) | |
| MNSI Score | 4990 | 2.0 (2.5) | 4997 | 2.0 (2.5) 0 | |
|
| |||||
| N | Frequency (%) | N | Frequency (%) | ||
|
| |||||
| Categorical Factors | Macroalbuminuria | 5071 | 327 (6) | 5083 | 339 (7) |
| Microalbuminuria | 4732 | 1264 (27) | 4756 | 1241 (26) | |
| History of photocoagulation or vitrectomy | 5090 | 428 (8) | 5106 | 466 (9) | |
| History of cataract removal | 5091 | 574 (11) | 5107 | 576 (11) | |
| Number of eyes with blindness | 5014 | 5023 | |||
| One | 129 (3) | 139 (3) | |||
| Two | 15 (0) | 16 (0) | |||
| MNSI score >2.0 | 5095 | 2160 (42) | 5106 | 2185 (43) | |
| Vibratory sensation loss | 5070 | 683 (13) | 5076 | 694 (14) | |
| Ankle jerk loss | 5049 | 1599 (32) | 5053 | 1648 (33) | |
| Loss of light touch | 5075 | 300 (6) | 5081 | 330 (7) | |