Table 1.
Characteristics of cases using surgical resection vs nonsurgical ablations
| Ref. | Treatment | M/F | Mean tumor size (cm) | Mean age (yr) | Mean AFP (ng/mL) | Child-Pugh A/B | Mean follow-up (mo) |
| Huang et al[9] | PEI | 19/19 | ≤ 2.0 (n = 21) | 63 ± 10.9 | > 200 (n = 7) | 29/3 | 37.7 ± 14.5 |
| RES | 27/11 | ≤ 2.0 (n = 24) | 59 ± 11.4 | > 200 (n = 8) | 28/0 | 38.4 ± 16.4 | |
| Chen et al[10] | RFA | 56/15 | ≤ 3.0 (n = 37) | 51.9 ± 11.2 | > 200 (n = 31) | 71/0 | 27.9 ± 10.6 |
| RES | 75/15 | ≤ 3.0 (n = 42) | 49.4 ± 10.9 | > 200 (n = 30) | 90/0 | 29.2 ± 11.9 | |
| Huang et al[11] | RFA | 85/30 | ≤ 3.0 (n = 45) | 55.91 ± 12.68 | > 400 (n = 32) | 106/9 | 37.2 (6.0-60) |
| RES | 79/36 | ≤ 3.0 (n = 57) | 56.57 ± 14.30 | > 400 (n = 21) | 110/5 | 46.4 (1.2-60) | |
| Feng et al[12] | RFA | 79/5 | ≤ 2.0 (n = 31) | 51 (24-83) | 215.5 (0.5-8530) | 39/45 | 36 |
| RES | 75/9 | ≤ 2.0 (n = 25) | 47 (18-76) | 262.8 (1.7-10220) | 43/41 | 36 | |
| Cho et al[13] | PEI | 86/30 | ≤ 2.0 (n = 43) | 58.0 ± 9.7 | > 20 (n = 47) | 92/24 | 68 |
| RES | 91/25 | ≤ 2.0 (n = 43) | 56.0 ± 8.9 | > 20 (n = 47) | 92/24 | 68 | |
| Abu-Hilal et al[14] | RFA | 27/7 | 3.8 (1.3-5) | 65 | - | 27/7 | 30 (0-60) |
| RES | 26/8 | 3.0 (2-5) | 67 | - | 25/9 | 43 (2-129) | |
| Ueno et al[15] | RFA | 100/55 | 2.7 ± 0.1 | 66 (40-79) | 131 ± 33 | - | 36.8 ± 1.5 |
| RES | 82/41 | 2.0 ± 0.1 | 67 (28-85) | 382 ± 108 | - | 35.0 ± 1.7 | |
| Kagawa et al[16] | RFA + TACE | 39/23 | ≤ 2.0 (n = 19) | 67.5 ± 8.4 | > 400 (n = 5) | - | 49 (1-102) |
| RES | 40/15 | ≤ 2.0 (n = 9) | 66.1 ± 8.4 | > 400 (n = 10) | - | 50 (9-95) | |
| Nishikawa et al[17] | RFA | 95/67 | 1.99 ± 0.62 | 68.4 ± 8.7 | 74.7 ± 181.1 | 102/22 | 37.2 (2.4-84) |
| RES | 50/19 | 2.68 ± 0.49 | 67.4 ± 9.7 | 376 ± 1989.8 | 45/5 | 39.6 (8.4-84) | |
| Guo et al[18] | RFA | 78/16 | ≤ 3.0 (n = 62) | 56 (19-75) | > 200 (n = 34) | 63/31 | 28 (7-75) |
| RES | 94/8 | ≤ 3.0 (n = 75) | 51.5 (18-75) | > 200 (n = 34) | 95/7 | 32 (6-86) | |
| Kim et al[19] | RFA + TACE | 31/6 | 3.46 ± 0.75 | 61.7 ± 11.1 | ≥ 100 (n = 7) | 37/0 | 29.9 ± 7.8 |
| RES | 36/11 | 3.66 ± 0.76 | 58.8 ± 10.7 | ≥ 100 (n = 14) | 45/2 | 31.7 ± 10 | |
| Lai et al[20] | RFA | 19/12 | 1.8 ± 0.6 | 63.1 ± 12.8 | 201.3 (2-2221.9) | - | 35.1 ± 17.4 |
| RES | 55/25 | 2.9 ± 1.1 | 60.8 ± 9.9 | 256.5 (91.5-5193) | - | 29.7 ± 19.9 |
RES: Resection; RFA: Radiofrequency ablation; PEI: Percutaneous ethanol injection; TACE: Transcatheter arterial chemoembolization; M: Male; F: Female; AFP: Alpha-fetoprotein.