Table 2.
Ref. | Treatment | M/F | Mean tumor size (cm) | Mean age (yr) | Mean AFP (ng/mL) | Child-Pugh A/B | Mean follow-up (mo) |
Brunello et al[21] | PEI | 49/30 | 2.25 ± 0.54 | 70.3 ± 8.1 | 16.5 (MD) | 39/30 | 25.3 (MD) |
RFA | 43/27 | 2.42 ± 0.49 | 69.0 ± 7.7 | 22.0 (MD) | 39/31 | 26.1 (MD) | |
Lin et al[22] | PEI | 34/18 | 2.8 ± 0.9 | 67 ± 6.0 | > 400 (n = 8) | 39/12 | 23.8 ± 10.4 |
RFA | 35/17 | 2.9 ± 0.8 | 59 ± 10 | > 400 (n = 7) | 41/11 | 24.5 ± 11.3 | |
Shiina et al[23] | PEI | 87/27 | ≤ 2.0 (n = 57) | ≤ 65 (n = 41) | > 400 (n = 7) | 85/29 | 2.9 (MD) |
RFA | 79/39 | ≤ 2.0 (n = 45) | ≤ 65 (n = 45) | > 400 (n = 6) | 85/33 | 3.1 (MD) | |
Lin et al[24] | PEI | 39/23 | 2.3 ± 0.8 | 60 ± 8 | 400 (n = 9) | 47/15 | 26 ± 12 |
RES | 30/22 | 2.5 ± 1.0 | 61 ± 10 | 400 (n = 10) | 46/46 | 28 ± 12 | |
Lencioni et al[25] | PEI | 30/20 | 2.8 ± 0.8 | 69 ± 7.4 | 54 (MD) | 35/15 | 22.4 ± 8.6 |
RFA | 36/16 | 2.8 ± 0.6 | 67 ± 6.0 | 57 (MD) | 45/7 | 22.9 ± 9.4 |
PEI: Percutaneous ethanol injection; RFA: Radiofrequency ablation; M: Male; F: Female; AFP: Alpha-fetoprotein; MD: Median; RES: Resection.