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. 2014 Aug 7;20(29):9633–9652. doi: 10.3748/wjg.v20.i29.9633

Table 3.

Degree of telaprevir and boceprevir resistance associated mutations

Degree of resistance Mutations Fold increase
Low level V36A/M/C 3.5-7
T54A/S 6-12
R155K/T/Q 8.5-11
Intermediate V36A/M + R155K/T 57-71
High level A156V/T 74-410
V36A/M + A156V/T > 700