Table 3.
Factors independently associated with AKI after adjustment for confounders (stepwise logistic regression)
| Variable | OR (95% CI) | P Value |
|---|---|---|
| Respiratory statusa | ||
| No MV (reference) | ||
| MV, no ARDS | 4.34 (3.71 to 5.10) | <0.001 |
| ARDS | 11.01 (6.83 to 17.73) | <0.001 |
| Age (per yr) | 1.04 (1.03 to 1.04) | <0.001 |
| Chronic cardiac dysfunctionb | 1.54 (1.30 to 1.82) | <0.001 |
| Chronic liver diseaseb | 1.41 (1.14 to 1.76) | <0.001 |
| Immunodeficiencyb | 1.68 (1.45 to 1.76) | 0.002 |
| Shock | 4.23 (3.38 to 5.29) | <0.001 |
| Diabetes mellitus | 1.62 (1.38 to 1.90) | <0.001 |
| Multiple myeloma | 1.91 (1.01 to 3.61) | <0.001 |
Hosmer–Lemeshow statistics were as follows: κ2=11.8; P=0.16; C statistic: 0.77. OR, odds ratio; 95% CI, 95% confidence interval; MV, mechanical ventilation.
Respiratory status was inserted as the dummy variable.
Underlying comorbidities (chronic liver disease, chronic cardiac dysfunction, or immunodeficiency) were defined according to the Knaus definition (40).