Table 2.
Clinical characteristics of patients with and without upper gastrointestinal bleeding
| Patients' Characteristics | Upper Gastrointestinal Bleeding (−; n=2584) | Upper Gastrointestinal Bleeding (+; n=384) | P Value |
|---|---|---|---|
| Age, yr | 67±19 | 68±17 | 0.02 |
| Men, n (%) | 1399 (54.1) | 215 (56.0) | 0.46 |
| Follow-up, yr | 1.9 (2.5) | 1.8 (2.4) | 0.99 |
| Underlying disease | |||
| Diabetes mellitus | 761 (36.9) | 143 (45.7) | 0.002 |
| Chronic GN | 671 (32.6) | 94 (30.0) | 0.53 |
| Hypertension | 314 (15.2) | 25 (8.0) | 0.001 |
| History of upper gastrointestinal bleeding | 160 (6.2) | 66 (17.2) | <0.001 |
| H. pylori infection | 54 (2.1) | 72 (18.8) | <0.001 |
| Coronary artery disease | 318 (12.3) | 57 (14.8) | 0.16 |
| Nonsteroidal anti-inflammatory drugs | 132 (5.2) | 23 (6.0) | 0.47 |
| Aspirin | 300 (11.5) | 45 (11.7) | 0.95 |
| Warfarin | 52 (2.0) | 12 (3.1) | 0.16 |
| eGFR, ml/min per 1.73 m2 | 18.4±23.0 | 13.9±16.8 | <0.001 |
| Body mass index, kg/m2 | 23.9±4.9 | 23.9±5.1 | 0.40 |
| Systolic BP, mmHg | 136±25 | 140±26 | 0.08 |
| Diastolic BP, mmHg | 80±15 | 80±14 | 0.23 |
| Hemoglobin, g/dl | 10.3±3.2 | 9.9±2.8 | <0.001 |
| Platelet count, 1000/μl | 203 (86–221) | 205 (170–241) | 0.92 |
| BUN, mg/dl | 42±38 | 49±38 | <0.001 |
| Creatinine, mg/dl | 2.9±3.3 | 3.6±3.6 | <0.001 |
| Uric acid, mg/dl | 8.1±2.6 | 8.3±2.8 | 0.08 |
| Calcium, mg/dl | 9.1±0.7 | 8.9±0.8 | 0.04 |
| Phosphorus, mg/dl | 4.7±1.7 | 4.9±1.6 | 0.04 |
| Albumin, g/dl | 3.5±0.8 | 3.3±0.8 | <0.001 |
| Cholesterol, mg/dl | 183 (157–216) | 179 (149–210) | 0.34 |
| Triglyceride, mg/dl | 126 (89–183) | 128 (90–185) | 0.50 |
| Fasting blood glucose, mg/dl | 112 (97–143) | 123 (102–160) | 0.03 |
Data are reported as mean±SD, median (interquartile range), or frequency (percentage).