Table 2.
Histologic Parameter | PE (n=11) | PC (n=25) | HC (n=14) | NPC (n=13) | P Value |
---|---|---|---|---|---|
Acute tubular necrosis | 0 (0) | 4 (16) | 3 (21) | 3 (23) | 0.41 |
Congestion | 0 (0) | 0 (0) | 0 (0) | 3 (23) | 0.01 |
Endotheliosis | 6 (55) | 3 (12) | 2 (14) | 0 (0) | 0.003 |
<20% of the lumen | 1 (17) | 3 (100) | 1 (50) | NA | |
20%–80% of the lumen | 3 (50) | 0 | 1 (50) | NA | |
>80% of the lumen | 2 (33) | 0 | 0 | NA | |
FSGS | 1 (9) | 2 (8) | 5 (36) | 0 (0) | 0.03 |
Global sclerosis>1% | 1 (9) | 0 (0) | 5 (36) | 1 (8) | 0.04 |
Glomerulitis | 0 (0) | 6 (24) | 1 (7) | 2 (15) | 0.23 |
Hyalinosis | 1 (9) | 4 (16) | 7 (50) | 10 (77) | <0.001 |
Interstitial fibrosis tubular atrophy | 0 (0) | 0 (0) | 2 (14) | 0 (0) | 0.06 |
Intima fibrosis | 2 (18) | 7 (28) | 11 (79) | 5 (39) | 0.01 |
Ischemia | 0 (0) | 1 (4) | 3 (21) | 1 (8) | 0.17 |
Mesangium changes | 1 (9) | 0 (0) | 4 (29) | 1 (8) | 0.04 |
Microthrombi | 1 (9) | 0 (0) | 1 (7) | 0 (0) | 0.20 |
Edema | 1 (9) | 0 (0) | 0 (0) | 1 (8) | 0.34 |
Podocyte changes | 2 (18) | 0 (0) | 0 (0) | 0 (0) | 0.02 |
Tram tracking | 4 (36) | 0 (0) | 0 (0) | 0 (0) | <0.001 |
Values are expressed as n (%). All patients with FSGS were classified as the “not otherwise specified” variant.