Table 2.
Differential expression data for genes encoding key IRFs in HIV-1–treated MDDCs
| Symbol | Accession no. | 6 Hours | 24 Hours | 48 Hours |
|---|---|---|---|---|
| IRF-1 | NM_002198 | 2.7 ± 0.9 | 4.6 ± 1.0 | 7.4 ± 1.2 |
| IRF-2 | NM_002199 | No change | 1.7 ± 0.2 | 2.7 ± 0.7 |
| IRF-3 | NM_001571 | No change | No change | No change |
| IRF-4 | NM_002460 | No change | 3.9 ± 1.0 | 4.4 ± 0.9 |
| IRF-7 | NM_004031 | 3.9 ± 0.25 | 5.0 ± 0.7 | 4.9 ± 1.6 |
| IRF-8 | NM_002163 | 8.9 ± 3.7 | 2.7 ± 0.7 | 1.2 ± 0.1 |
| IRF-9 | NM_006084 | No change | 3.8 ± 0.6 | 1.8 ± 0.7 |
Day 6 MDDCs were mock-treated or treated with HIV-1BaL (MOI, 10), and IRF gene expression was determined by qPCR. Data are mean fold change ± SE in the expression of IRF genes in HIV-1–treated cells at 6, 24, and 48 hours after treatment from 4 independent experiments.