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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Apr 10;34(6):1179–1186. doi: 10.1161/ATVBAHA.114.303326

Figure 3.

Figure 3

In situ zymography for collagenolytic activity in mouse arteries. Representative sections of aortic roots of mutant mice after 24 weeks of atherogenic diet incubated with a fluorescent collagenase-activatable probe in presence or in absence of the broad MMP inhibitor ilomastat (A). Quantification of the mean fluorescence in the intima (B) and the mean fluorescence ratio compared to ilomastat treated samples (C) are represented (n=5). Bars represent mean ± SEM (*p<0.05, **p<0.01, ***p<0.001).