Table 1.
Material demographics
| Normal weight | Obese | P value | |
|---|---|---|---|
| Number | 38 | 23 | |
| Prepregnancy BMI, kg/m2 | 22.0±1.8 | 35.5±4.0 | |
| Age, years | 32.8±5.9 | 30.2±4.5 | 0.06 |
| Parity, % | 0.11 | ||
| 1 | 66 | 43 | |
| 2 or 3 | 34 | 57 | |
| Ethnicity, % | 0.01 | ||
| Caucasian | 71 | 35 | |
| African-American | 11 | 39 | |
| Hispanic | 11 | 22 | |
| Asian | 8 | 4 | |
| Education (college degree), % | 87 | 56 | <0.01 |
| C-section, % | 26 | 48 | 0.10 |
| Gestational weight gaina, lbs | 33.7±9.4 | 29.3±13.0 | 0.16 |
| 1-hour 50-gram GCT, mg/dl | 98.4±14.3 | 108.0±14.3 | 0.01 |
|
| |||
| Fasting sample at 36–38 weeks of gestation | |||
| Number | 33 | 15 | |
| Glucose, mg/dl | 80.9±6.5 | 86.7±8.7 | 0.03 |
| Triglycerides, mg/dl | 192.3±62.7 | 211.1±51.8 | 0.28 |
| C-peptide, ng/ml | 2.4±1.0 | 4.4±2.0 | <0.01 |
| Leptin, ng/ml | 25.0±12.7 | 54.2±14.5 | <0.01 |
| Adiponectin, μg/ml | 10.8±4.3 | 9.6±4.2 | 0.34 |
Data displayed as means ± SD. A multivariate logistic regression analysis was conducted allowing all of the variables that are significant above to come into the model to predict neonatal adiposity. The only significant variable at P < 0.05 in the multivariate analysis was maternal leptin with P = 0.0012.
a
The mean gestational age at the last prenatal visit was 39.14 weeks for both groups.