Table 3.
Data stratified by maternal leptin level
| Leptin <30.5 ng/ml | Leptin ≥30.5 ng/ml | P value | |
|---|---|---|---|
| Number | 24 | 24 | |
| Prepregnancy BMI, kg/m2 | 23.2±4.7 | 29.8±7.7 | <0.001 |
| Gestational weight gain, lbs | 30.3±6.1 | 35.8±13.9 | 0.08 |
|
| |||
| Maternalfasting sample | |||
| Glucose, mg/dl | 80.0±5.8 | 85.5±28.3 | 0.01 |
| C-peptide, ng/ml | 2.0±0.4 | 4.0±1.8 | <0.001 |
| Leptin, ng/ml | 18.4±7.7 | 49.7±12.8 | |
| Triglycerides, mg/dl | 182.0±65.9 | 214.4±48.7 | 0.06 |
| Adiponectin, μg/ml | 12.0±4.3 | 8.9±3.8 | 0.009 |
|
| |||
| Neonatal anthropometrics | |||
| Male gender, % | 41.7 | 45.8 | 0.78 |
| Length, cm | 50.5±1.6 | 51.0±2.4 | 0.41 |
| Weight, kg | 3.37±0.46 | 3.55±0.64 | 0.29 |
| Fat mass, kg | 0.38±0.15 | 0.48±0.19 | 0.06 |
| Body fat, % | 11.1±3.5 | 13.2±3.2 | 0.035a |
|
| |||
| Cord blood biomarkers | |||
| Glucose, mg/dl | 80.0±25.3 | 83.5±16.4 | 0.60 |
| C-peptide, ng/ml | 0.9±0.3 | 1.2±0.7 | 0.031a |
| Leptin, ng/ml | 7.6±3.9 | 12.5±7.0 | 0.006a |
| Adiponectin, μg/ml | 36.2±5.9 | 38.7±10.4 | 0.34 |
Data are displayed as means ± SD. There were no significant differences in maternal age, parity, ethnicity, delivery type, maternal education, gestational age, or gender of the newborn between the 2 groups.
a
Adjustment for gestational weight gain did change the significance.