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Sirius Red stained histological sections. (a, b) Nonirradiated-NIC groups presenting interlaced less compacted type I and III collagen fibers. (c) Irradiated-IC and (d) vehicle groups-IV showing dense disposition of parallel-arranged type I collagen fibers. (e) 10% and (f) 15% formulations presenting morphological and architectural collagen deposition pattern resembling that observed in the normal dermis (Sirius Red/Polarization Light, 400x magnification).
