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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: Circ Res. 2007 Jun 21;101(3):277–285. doi: 10.1161/CIRCRESAHA.107.155630

Figure 8.

Figure 8

Mediation of TGFβ/BMP signaling through Smad4-dependent and Smad4-independent pathways. Our data showed that Smad4 is required for proper AV cushion alignment and myocardial cell proliferation and survival. Nmyc is a direct target of Smad4 in the myocardium during embryogenesis.