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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Br J Haematol. 2014 Feb 26;165(5):640–648. doi: 10.1111/bjh.12801

Table II. PCNSL survival analysis based on expression of HGAL, LMO2 and BCL6 proteins.

Variable PFS PFS OS OS
Hazard ratio (95% CI) p-value Hazard ratio (95% CI) p-value
HGAL
  Negative (reference) 1.0 0.99 1.0 0.76
  Positive 1.0 (0.45 – 2.22) 0.89 (0.42 – 1.88)
LMO2
  Negative (reference) 1.0 0.071 1.0 0.027
  Positive 0.50 (0.23 – 1.06) 0.44 (0.21 – 0.91
BCL6
  Negative (reference) 1.0 0.006 1.0 0.055
  Positive 0.35 (0.16 – 0.74) 0.49 (0.24 – 1.02)
LMO2/BCL6 combined
 Double negative (reference) 1.0 0.004 1.0 0.006
 One marker positive 0.37 (0.15 – 0.90) 0.31 (0.12 – 0.77)
 Double positive 0.24 (0.10 – 0.61) 0.32 (0.13 – 0.75)

PFS, progression-free survival; OS, overall survival