Table 2.

Regional Aeration and Regional and Global Tidal Strain

Regional Variables:	High-Strain		High-Strain LPS		Low-Strain LPS
	Baseline	End	Baseline	End	Baseline	End
FEE	0.45 ± 0.14 a	0.41 ± 0.14 a	0.50 ± 0.16 a	0.42 ± 0.17 a	0.69 ± 0.08	0.60 ± 0.12
ΔFEE	−0.04 ± 0.08 b		−0.08 ± 0.10 b		−0.09 ± 0.10 b
FEI	0.62 ± 0.12 a	0.59 ± 0.14	0.67 ± 0.16	0.57 ± 0.21	0.74 ± 0.08	0.65 ± 0.12
ΔFEI	−0.04 ± 0.05 b		−0.11 ± 0.14 b		−0.10 ± 0.10 b
sVol	1.21 ± 0.62a	1.22 ± 0.51a	1.26 ± 0.44 a	1.05 ± 0.58a	0.33 ± 0.17	0.29 ± 0.18
ΔsVol	0.02 ± 0.49		−0.21 ± 0.51		−0.05 ± 0.11
Global sVol	1.17 ± 0.49a	1.08 ± 0.23 a	1.06 ± 0.20 a	0.87 ± 0.31 a	0.31 ± 0.09	0.27 ± 0.13

F=fractional gas content; EE=end-expiration; EI=end-inspiration; Δ=change in parameter from baseline to end; sVol=tidal specific volume change (i.e., tidal strain); global sVol=sVol measured from whole-lung average F_EE and F_EI. Regional variables were compared between groups with a linear mixed-effects model including group as a fixed effect and random intercepts for each animal. Global sVol was compared between groups using ANOVA with Tukey-Kramer corrected post-hoc tests.

^ap<0.01 vs. Low-Strain LPS group.

^bp<0.01 for the hypothesis that the variable equals 0.