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. 2014 Apr 17;35(8):1760–1764. doi: 10.1093/carcin/bgu093

Table II.

mtDNA copy number by characteristics of OPL patients and control subjects

Variables OPL patients Controls P a
n mtDNA copy number, mean (SD) n mtDNA copy number, mean (SD)
Overall 143 1.36 (0.74) 357 1.11 (0.32) <0.001
Sex
 Male 87 1.43 (0.87) 215 1.10 (0.33) <0.001
 Female 56 1.26 (0.47) 142 1.13 (0.29) 0.019
P a 0.203 0.312
Ageb
 ≤59 72 1.41 (0.89) 186 1.09 (0.27) <0.001
 >59 71 1.32 (0.57) 171 1.14 (0.36) 0.004
P a 0.446 0.133
Race
 Caucasians 126 1.33 (0.70) 323 1.11 (0.32) <0.001
 Others 17 1.60 (1.02) 34 1.10 (0.31) 0.012
P a 0.172 0.846
Smoking status
 Never 60 1.40 (0.81) 182 1.09 (0.27) <0.001
 Ever 83 1.34 (0.69) 175 1.13 (0.35) 0.002
P a 0.628 0.216
Pack-years in ever smokersc
 <20 20 1.51 (1.00) 92 1.10 (0.38) 0.003
 ≥20 44 1.27 (0.54) 83 1.17 (0.32) 0.179
P a 0.218 0.251
Alcohol consumptiond
 Never 53 1.36 (0.56) 249 1.11 (0.30) <0.001
 Ever 85 1.33 (0.76) 108 1.12 (0.35) 0.011
P a 0.792 0.892

aAll P values were determined by the Student’s t-test.

bThe median age in the control group was 59 years.

cPack-years were not available for 19 ever smokers.

dIn the OPL group, five patients did not answer the alcohol consumption question.