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Risk estimates of OPLs for mtDNA copy number
| mtDNA copy number | OPL patients (n = 143), n (%) | Controls (n = 357), n (%) | Adjusted OR (95% CI)a | P |
|---|---|---|---|---|
| By median | ||||
| <1.08 | 56 (39.2) | 186 (52.1) | 1.00 (ref.) | 0.004 |
| ≥1.08 | 87 (60.8) | 171 (47.9) | 1.93 (1.23–3.05) | |
aOR and 95% CI determined by unconditional multivariate logistic regression, adjusted for age, sex, race, pack-years and alcohol consumption.
