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. 2014 Apr 28;35(8):1807–1813. doi: 10.1093/carcin/bgu100

Fig. 3.

Fig. 3.

XNC10 silencing compromises in vivo tumor growth in semi-solid tumor grafts of syngeneic tadpoles. (A) Representative image of subcutaneous collagen grafts 7 days posttransplantation with either 5×105 15/0 WT (left) or shXNC10#7 (right) tumor cells in LG-15 tadpoles. (B) Area of XNC10-deficient compared to WT tumor graft at 4, 7, 10, 16, 24 and 34 days posttransplantation. Three independent experiments were performed with 3–9 animals per group. (C) H&E staining of cryosections of tumor collagen grafts 7 days posttransplantation. WT grafts; left two panels (I and II) and shXNC10#7 tumor grafts; right two panels (III and IV).